Bcl-2-Ome Submission Form

Submission of Data to Bcl-2-Ome

Additional database entries defining Bcl-2 family interactions or activation of Bax and Bak by BH3-only proteins can be provided either by filling out this form or by sending the information as xml file to
annika [dot] hantusch (at) uni-konstanz [dot] de.

For submission as xml, the structure of the xml file can be downloaded here.

Reviewing Process

The core requirements for acceptance of data in Bcl-2-Ome are that the data were published in peer-reviewed journals with sufficient experimental and methodological information to allow a thorough validation. Submissions are reviewed by the hosting institution and members of the Bcl-2 specific FOR2036 consortium, which are the groups of:

Prof. Dr. Thomas Brunner, University of Konstanz, Germany
Prof. Dr. Markus Morrison (Rehm), University of Stuttgart, Germany
Prof. Dr. Andreas Villunger, Biocenter Innsbruck Medical University, Austria
Prof. Dr. Thomas Kaufmann, University of Bern, Switzerland
Prof. Dr. Christoph Borner, University of Freiburg, Germany
Prof. Dr. Georg Häcker, University of Freiburg, Germany
Prof. Dr. Ana J. García Sáez, University of Tübingen, Germany
PD Dr. Alexander Egle, University Hospital Salzburg, Austria
Dr. Miriam Erlacher, University Hospital Freiburg, Germany
PD Dr. Philipp Jost, Technical University Munich, Germany

Additional data reviewers can apply for this role by contacting Annika Hantusch.

Bcl-2-Ome Submission Form

Fields marked with * are required for submission.

Personal information: First name*:

Last name*:

Institute*:

E-Mail*:

Protein1*:

Protein2*:

Reference:

Author:

Year:

DOI*:

Figure*:

Type*:

Qualitative Quantitative
Interaction Effector activation
Interaction/Activation detected*: True False
Organism*:

Cell type*:

Instrument: (e.g. Biacore S51 biosensor)

Description:

Kd (nM): (please specify, if applicable)

kon (M-1s-1): (please specify, if applicable)

koff (s-1): (please specify, if applicable)

IC50 (nM): (please specify, if applicable)

SD (nM): (please specify, if applicable)

Antibody1: (e.g. anti-Bim, 3C5 Enzo Biochem Inc.)
(Used for immunoprecipitation in case of CoIP)

Antibody2: (e.g. anti-Bcl-2, 3F11 Dana-Farber Cancer Institute Boston MA)
(Used for immunoblotting in case of CoIP)

Detergent: (e.g. CHAPS)

Protein Details:
Protein*:

Chimeric: False True
Concentration (nM): (e.g. 1000)

Sequence origin*:

Fulllength: False True
Recombinant*:


Additional information you would like to specify: